ORGANIZATIONAL CAPACITIES OF NATIONAL PHARMACOVIGILANCE CENTRES IN AFRICA: ASSESSMENT OF RESOURCE ELEMENTS ASSOCIATED WITH SUCCESSFUL AND UNSUCCESSFUL PHARMACOVIGILANCE EXPERIENCES

Organizational capacities of national pharmacovigilance centres in Africa: assessment of resource elements associated with successful and unsuccessful pharmacovigilance experiences

Abstract Background National pharmacovigilance centres (national centres) are gradually gaining visibility as part of the healthcare delivery system in Africa.As does happen in high-income countries, it is assumed that national centres can play a central coordinating role in their national pharmacovigilance PR783 (PV) systems.However, there are no

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Identification of deubiquitinase inhibitors via high-throughput screening using a fluorogenic ubiquitin-rhodamine assay

Summary: Identification of selective deubiquitinase (DUB) inhibitors is critical for probe development to further understand and explore DUB biological function.Here, we detail the optimization and deployment of an in vitro fluorogenic ubiquitin-rhodamine PR783 assay to conduct high-throughput screening of a small molecule library against a panel o

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OWL2Go: Auto-generation of Go data models for OWL ontologies with integrated serialization and deserialization functionality

The Web Ontology Language (OWL) is a formal language for the description of terms and their relationship in a certain domain.It enables information exchange among heterogeneous applications and devices in Fan Grill a machine-readable format.However, in software development the usage of data models is common.In order to facilitate the usage of ontol

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Food intolerance in patients with functional abdominal pain: Evaluation through endoscopic confocal laser endomicroscopy

Background and study aims Gastrointestinal symptoms assumed to be caused by food intolerance are reported frequently in the general population.There is a significant difference EMPTY VEG CAPS "00" between self-reported and objective proven food intolerance, as shown by placebo-controlled, double-blind, randomized trials.This discrepancy may be over

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